MIF: Most Interesting Factor

In recent years, researchers have identified a pivotal upstream role for macrophage migration inhibitory factor (MIF) in the innate immune response. The pioneering book describes this renaissance of knowledge in the biology of MIF. Topics covered include MIF's molecular mechanism of action its counter regulatory action on the immunosuppressive properties of glucocorticoids, its role in the production of proinflammatory mediators as shown in cell-based and animal studies; and its central role in human inflammation