Biophysical Techniques in Drug Discovery

Biophysical techniques are used in many key stages of the drug discovery process including screening of new ligands for a certain receptor, characterisation of a drug mechanism and validation of data from biochemical and cellular assays. This title, with contributions from both academia and industry, brings together the different elements of biophysical techniques within drug discovery in a single volume. Topics covered include the characterisation of integral membrane proteins and their interactions with drugs, G protein-coupled receptors and important developments in the field such as improvement in electron microscopy resolution.