Computational Systems Pharmacology and Toxicology

This book presents systems pharmacology and toxicology approaches to computational toxicology, linking chemical exposures to genes, diseases and complex biological pathways. It discusses new methods to study chemical and biological target elucidation and computational models. These computational tools hold tremendous promise for advancing applied and basic science, streamlining drug efficacy and safety testing, reducing the use of animals in testing, and increasing the efficiency and effectiveness of risk assessment for environmental chemicals. This timely and modern book will be of interest to risk assessors as well as toxicologists and pharmacologists. The case study section will make it particularly useful for academic course work at graduate and undergraduate level.