PCR Mutation Detection Protocols

This volume provides biological and clinical investigators with a comprehensive collection of contemporary PCR-based screening methods suitable for detecting the presence of both known and novel mutations. The methods cover point mutations, deletions and non-sense mutations. The techniques of DNA array analysis, along with such experimental methods as conformation-sensitive gel electrophoresis, are also included. Each chapter explains the basic theory behind the technique and provides valuable notes essential for its successful execution.