When Cells Die : A Comprehensive Evaluation of Apoptosis and Programmed Cell Death

This is an integrated and cross-disciplinary presentation of cell death research. It emphasises the pervasiveness of the phenomena and its importance in development, homeostasis, aging and disease. Encompassing the phenomena from genetics to signal transduction and observed manifestation, and presenting the work through model systems of life-forms ranging from nematodes to humans, the authors discuss the similarity and means of observing and studying the apoptotic and other forms of cell death. Emphasis is placed on the evaluation of the many indicators of cell death and on connecting the growing stories of cell death into a coherent framework.