Handbook of Natural Toxins Volume 8 : Bacterial Toxins

Detailing the diverse ways bacterial toxins subvert cellular metabolism and signalling, this state-of-the-art reference describes the structure and function of bacterial toxins and presents a comprehensive review of virulence factors-providing the latest information concerning cell physiology and biochemistry, as well as new toxin tools for experimental studies and clinical therapy. Containing expert contributions from more than 50 internationally acclaimed authorities in their respective fields, Volume 8: Bacterial Toxins and Virulence Factors in Disease delineates the common features of bacterial toxins with ADP-ribosylating activity ... reviews the biosynthesis and function of diphthamide in elongation factor 2 ... investigates the biogenesis of toxins responsible for causing cholera and related diarrheal diseases ... covers the pathogenicity of Escherichia coli bacteria at the molecular level... elucidates the physicochemical and biological characteristics of Clostridium difficile toxins... examines the mechanisms by which pertussis toxin is synthesized, assembled, secreted, and introduced into eukaryotic cells ... explores the role of bacterial toxins in septic shock... and more. Book jacket.