Sickle Cell Disease : Pathophysiology, Diagnosis, and Management

Sickle cell disease is a complex disease with a genetic mutation producing a wide variety of manifestations. It is of great public health importance nationally and internationally. While the conclusions of this study support the generally accepted view on the disease, the book also provides the most recent information and state-of-the-art knowledge on the subject. It presents the genetic, molecular, cellular, metabolic, rheologic, clinical, diagnostic, therapeutic and psychosocial dimensions of sickle cell disease. Its synthesis of micro to macro, molecular to cellular, individual to social relationships provides a comprehensive study of the disease.